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Deficient Activity of Mitochondrial Flavine Adenine Dinucleotide-Linked Glycerophosphate Dehydrogenase in Pancreatic Islet Beta Cells as a Determinant of Non-Insulin-Dependent Diabetes MellitusExtensive experimental investigations in animal models of diabetes mellitus have led to the proposal that a deficient activity of mitochondrial flavine adenine dinucleotide (FAD)-linked glycerophosphate dehydrogenase represents...
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Myelolipomatous Adrenal Adenoma and Adrenal ScintigraphyAdrenal myelolipomas are usually benign and non-functioning masses. On the other hand, adrenal myelolipomatous adenoma that may mimic adrenal myelolipoma on conventional imaging may be a rare cause of subclinical Cushing’s disease.
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Autonomic Diabetic Neuropathy Impairs Glucose and Dipeptidyl Peptidase 4 Inhibitor-Regulated Glucagon Concentration in Type 1 Diabetic Patientsipeptidyl peptidase 4 inhibitors (DPP4i) could exert their glucagonostatic action through a functional autonomic nervous system independently from insulin secretion.
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Olfactory Sulcus Hypoplasia Images of a Case With Kallmann SyndromeKallmann syndrome is a form of hypogonadotropic hypogonadism accompanied by anosmia or hyposmia. MR images of midline defects in Kallmann syndrome were rarely seen in the literature.
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Serologic Screening of Celiac Disease in Patients With Type 1 DiabetesType 1 diabetes mellitus (T1DM) is an autoimmune disorder associated with increased risk of additional autoimmune diseases (ADs) as celiac disease (CD). The aim of this study was to investigate the prevalence of CDs in a population of diabetic children along with the presence of any suggestive clinical signs and symptoms of CD and any effects of CD on the patients’ diabetic control and growth.
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Viewpoints |
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Non-nutritive sweeteners (NNSs) gained attention as dietary tools that provide a free sweet taste of energy to foods. However, its health benefits have been questioned. The aim of this review is to present and discuss the effects of NNSs on energy and glycemic homeostasis, as well as the mechanisms involved. Full Text | Outpatient Endocrine Diagnosis and Treatment of Thyroid Diseases and Disorders in a Portuguese Public University Hospital Thyroid diseases and disorders account for most of the activity of outpatient endocrine departments, but objective data regarding the care of such patients is difficult to find. Knowledge of that data would be fundamental for the planning of those departments and to develop translational research. Full Text | |||
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A Case of Mitochondrial Disease First Diagnosed Over 30 Years After Onset
Mitochondrial disease is induced by mutations in both mitochondrial DNA and DNA of nuclear genes that encode mitochondrial proteins, and there is a general lack of genotype-phenotype correlation in many mitochondrial disorders, which makes the diagnosis of mitochondrial disease difficult. We treated a 37-year-old woman with congenital cataract, bilateral sensory deafness, severe bilateral ptosis, oculomotor disorder in all directions and systemic muscular atrophy and weakness. Full Text
| Current Issue |
Past IssuesVol. 9, No. 1-2, Apr 2019
Table of Contents
Editorial
| Anti-Atherogenic Properties of Extra Virgin Olive Oil | Abstract HTML PDF |
| Hidekatsu Yanai | 1-2 |
| doi: https://doi.org/10.14740/jem509w |
Original Article
| Outpatient Endocrine Diagnosis and Treatment of Thyroid Diseases and Disorders in a Portuguese Public University Hospital | Abstract HTML PDF |
| Joao Martin Martins, Dinis Reis, Lucas Batista, Filipa Parames, Margarida Mendes de Almeida, Guilhermina Cantinho | 3-17 |
| doi: https://doi.org/10.14740/jem550 |
| Effects of Metformin Monotherapy on Metabolic Parameters in Japanese Patients With Type 2 Diabetes | Abstract HTML PDF |
| Hisayuki Katsuyama, Hidekatsu Yanai | 18-21 |
| doi: https://doi.org/10.14740/jem549 |
| Selenium Treatment Effect in Auto-Immune Hashimoto Thyroiditis in Macedonian Population | Abstract HTML PDF |
| Nevena Manevska, Sinisa Stojanoski, Tanja Makazlieva | 22-28 |
| doi: https://doi.org/10.14740/jem551 |
| The Prevalence of Eyesight Deterioration in People Aged Over 50 Years and Its Correlation With Type II Diabetes in Trinidad | Abstract HTML PDF |
| B. Shivananda Nayak, Joshua Ramoutar, Satesh Ramkesson, Varisa Ramkissoon, Tarun Ramlogan, Johann Ramnarine, Shania Ramnarine, Sharvana Ramoutar, Kesley Rampersad | 29-32 |
| doi: https://doi.org/10.14740/jem553 |
Case Report
| Two Cases of Mitochondrial Diabetes in Which Pancreatic Beta-Cell Function and Neuropathy Were Improved by Glucagon-Like Peptide-1 Receptor Agonist Therapy | Abstract HTML PDF |
| Midori Minezaki, Ichiro Abe, Monami Koga, Kaoru Sugimoto, Kaori Takeshita, Saori Takahara, Midori Nakagawa, Hideyuki Fujii, Hanako Ohishi, Tadachika Kudo, Kenji Ohe, Toshihiko Yanase, Kunihisa Kobayashi | 33-36 |
| doi: https://doi.org/10.14740/jem539 |