Central Diabetes Insipidus Diagnosed After Gynecologic Surgery: A Case Report

Nobuhiro Akuzawa, Naoyuki Harada, Noriko Hasegawa, Hidenori Seki, Yuko Oku, Masayuki Totsuka, Takashi Hatori, Atsushi Murakami, Kunihiko Imai, Yonosuke Kitahara, Masahiko Tashiro, Masahiko Kurabayashi


A 41-year-old woman with non-alcoholic fatty liver disease and complex endometrial hyperplasia with atypia was admitted to our hospital to undergo hysterectomy. Her weight was 107 kg, having doubled after delivery of her second child. After a routine hysterectomy, unexpected polyuria was observed. Investigation revealed a relatively low plasma vasopressin concentration, and absence of hyperintense signals in the region of the posterior lobe of the pituitary gland on T1-weighted magnetic resonance imaging, suggesting partial central diabetes insipidus. It was concluded that excessive intake of sweetened carbonated beverages due to thirst caused by diabetes insipidus had contributed to her obesity.

J Endocrinol Metab. 2013;3(1-2):41-46
doi: https://doi.org/10.4021/jem147e


Central diabetes insipidus; Magnetic resonance imaging; Obesity; Polyuria; Vasopressin

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