Effects of Consumption of Various Fatty Acids on Serum HDL-Cholesterol Levels

Hidekatsu Yanai, Norio Tada

Abstract


Since HDL is an anti-atherogenic lipoprotein which plays a role in reversing cholesterol transport from the peripheral tissues to the liver, low HDL-cholesterol (HDL-C) levels are associated with the development of cardiovascular diseases. We previously studied effects of intake of various dietary fat on serum HDL-C levels to make “Dietary Reference Intakes for Japanese 2015”, and found that the substitution of fatty acids (FAs) for carbohydrates is beneficially associated with HDL-C, monounsaturated FA (MUFA) intake may not affect HDL-C and trans FA (TFA) is significantly associated with reduction of HDL-C. Consumption of n-3 poly-unsaturated FA (PUFA) was favorably associated with HDL-C. Here we review meta-analyses on the effects of various FA consumption on serum HDL-C levels, to make “Dietary Reference Intakes for Japanese 2020”. Consumption of ruminant-TFA may not affect HDL; however, increased industrially produced TFA intake was associated with a significant decrease in HDL and a significant increase in LDL. An intake of n-3 PUFA and MUFA was associated with an increase of HDL. An intake of saturated FA (SFA) was associated with an increase of HDL; however, SFA was also associated with an increase of LDL.




J Endocrinol Metab. 2018;8(5):94-99
doi: https://doi.org/10.14740/jem534

Keywords


High-density lipoprotein; Monounsaturated fatty acids, Poly-unsaturated fatty acids; Saturated fatty acids; Trans fatty acids

Full Text: HTML PDF
 
Home     |     Log In     |      About     |      Search     |      Current     |      Archives     |      Submit      |     Subscribe


 

     

Aims and Scope

Current Issues

Conflict of Interest

About Publisher

Editorial Board

Archives

Copyright

Company Profile

Editorial Office

Misconduct and Retraction

Permissions

Company Registration

Contact Us

Abstracting and Indexing

ICMJE

Ownership

Instructions to Authors

Access

Declaration of Helsinki

Contact Publisher

Submission Checklist

Reprints

Terms of Use

Company Address

Submit a Manuscript

Open Access Policy

Privacy Policy

Browse Journals

Publishing Fee

Publishing Policy

Disclaimer

Recent Highlights

Peer-Review Process

Publishing Quality

Code of Ethics

Advertising Policy

Manuscript Tracking

Advanced Search

For Librarians

Careers

Publishing Process

Publication Frequency

For Reviewers

Propose a New Journal

       
       

Journal of Endocrinology and Metabolism, bimonthly, ISSN 1923-2861 (print), 1923-287X (online), published by Elmer Press Inc.        
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.jofem.org   editorial contact: editor@jofem.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

DECLARATION: THIS JOURNAL SITE OUTLOOK IS DESIGNED BY THE PUBLISHER AND COPYRIGHT PROTECTED. DO NOT COPY!