Mix of Allegedly Functional Components Improves Metabolic Syndrome Risk Factors

Sandra Maria Barbalho, Maricelma da Silva Soares de Souza, Patricia Cincotto dos Santos Bueno, Elen Landgraf Guiguer, Flavia Maria Vasques Farinazzi-Machado, Adriano Cressoni Araujo, Francelino Aparecido dos Santos, Gisele Cristina dos Santos, Ricardo Haddad Adad, Mariana Fonseca dos Santos, Claudemir Gregorio Mendes, Ricardo de Alvares Goulart, Daniel Pereira Coqueiro


Background: Food is one of the main factors that diminish the risk of development of chronic diseases in humans. In view of this fact, increasing attention has focused on the production and consumption of foods that help reduce this risk. Besides, metabolic syndrome risk factors are increasing in almost all populations of the world. Therefore, the objective of this work was to evaluate the effects of a mixture of ingredients containing textured soy protein, wheat bran, oats, black sesame seeds, white sesame seeds, brown linseed, granola and brown sugar on the biochemical profile, body weight and intestinal motility of Wistar rats.

Methods: The experiment involved male rats, which were divided into two groups: one that ingested the mix and the other a control group.

Results: After 40 days of treatment, it was found that body weight, total cholesterol, triglycerides, and glucose levels were reduced and HDL-c increased. Intestinal transit time was also improved.

Conclusion: It was concluded that the use of this mix had beneficial effects on the metabolic profile contributing to the prevention of metabolic syndrome risk factors and improved intestinal transit of Wistar rats.

J Endocrinol Metab. 2015;5(4):238-244
doi: http://dx.doi.org/10.14740/jem292w


Fibers; Lipemia; Glycemia; Intestinal motility; Wistar rats

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