The Development of Repeated Severe Hypothermia in a House in a Type 2 Diabetic Patient Complicated With Klinefelters Syndrome

Yoshinori Masui, Hidetaka Hamasaki, Akahito Sako, Sumie Moriyama, Reo Yoshikawa, Hiroki Adachi, Shuichi Mishima, Hidekatsu Yanai


Hypothermia is a condition in which body core temperature decreased below the temperature for normal physio-biochemical functions, which is defined as 35.0 oC. We experienced a male patient with type 2 diabetes and schizophrenia who developed severe hypothermia twice in his house, and we found that he has Klinefelters syndrome. To our knowledge, this is the first to report the association between hypothermia and Klinefelters syndrome. We discuss a possible association between low testosterone level and a single extra copy of the X chromosome in Klinefelters syndrome and the development of type 2 diabetes, schizophrenia and hypothermia.

J Endocrinol Metab. 2012;2(4-5):195-197


Hypogonadism; Hypothermia; Klinefelterís syndrome; Testosterone; Type 2 diabetes

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