A Review on Metabolic Syndrome

Abstract

The metabolic syndrome is described by the clustering of several risk factors for Type 2 diabetes and cardiovascular disease. Lipid disorder, obesity, diabetes in general and high blood pressure are collectively defined as risk factors for cardiovascular disease triggered by metabolic syndrome. The metabolic syndromes have a correlation with the variations in genetic susceptibility, nutritional regiment, physical exercise, chronological age and gender which play direct role in the incidence of metabolic syndrome and its side effects. There are several definitions of Metabolic Syndrome in the World: World Health Organization's (WHO), The NCEP Adult Treatment Panel (ATP) III and the International Diabetes Federation (IDF). It appears that the female type 2 diabetic patients need to change their life style to halt the burden of cardiovascular complications in type 2 diabetic patients. Clinicians should significantly consider screening all people regardless of age for abnormalities in glucose level. Early treatment in people with abnormal glucose level constitutes a strategy of preventing type 2 diabetes mellitus and metabolic syndrome. Studies about metabolic syndrome have shown that females were more affected than males. This may be due to the specific characteristics in the lifestyle changes between females and males diabetic patients. Postmenopausal status might be a predictor of metabolic syndrome. Some related factors of metabolic syndrome among postmenopausal women may increase cardiovascular risk in postmenopausal women.




J Endocrinol Metab. 2012;2(4-5):166-170
doi: https://doi.org/10.4021/jem118e