Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Original Article

Volume 8, Number 2-3, May 2018, pages 37-42

Serologic Screening of Celiac Disease in Patients With Type 1 Diabetes

Figures

Figure 1.
Figure 1. Prevalence of diabetic patients that have celiac seropositive results = 6.5% (9/138).
Figure 2.
Figure 2. Prevalence of celiac-seropositive patients among males (4/64) and females (5/74).
Figure 3.
Figure 3. Number of celiac seropositive patients who have celiac-related symptoms.

Tables

Table 1. Demographic Data (Total = 138, Male = 64, Female = 74)
 
VariableMinimumMaximumMeanStandard deviation
Age (years)1.0026.0016.535.62
Weight (kg)7.00133.0062.5223.38
Length (cm)75.00186.001.5720.30
BMI7.7748.2924.487.05
HbA1c value (%)6.4012.808.671.56
Triglycerides value (mg/dL)48430.002.10136.71
Cholesterol value (mg/dL)68.00400.002.1588.17
Fasting glucose value (mg/dL)51.00450.001.2052.33
Hemoglobin level (Hb)7.6717.0012.141.68

 

Table 2. The Significant Different Numerical Variables Between IgA Seropositive and Seronegative Diabetic Patients
 
IgA-TGAMeanSDP value
Age (years)No16.815.560.024
Yes12.445.25
Weight (kg)No63.8022.790.015
Yes44.2225.29
HbA1c value (%)No8.571.510.007
Yes10.001.62
Cholesterol value (mg/dL)No208.4387.030.001
Yes308.8936.56
BMINo24.847.0140.022
Yes19.305.56

 

Table 3. The Significant Difference of Categorical Variables Between IgA Seropositive and Seronegative Diabetic Patients
 
VariablesP value*
*Fisher exact P value.
Patient complain of eczema0.025
Patient diagnosed as eczema0.006
Family history of celiac disease0.004
Family history of DM 10.019

 

Table 4. Logistic Regression Showing the Predictor Variable for Seropositive Diabetic Patients
 
Categorical variableP-valueAOR*95% CI ( AOR)
LowerUpper
*Adjusted odd ratio.
Patient’s diagnosis of eczema0.00632.6622.675398.846
Family history of T1DM0.0415.7941.07231.328

 

Table 5. Linear Regression for Numerical Variables Associated With IgA Seropositivity
 
VariableAOR*95% CI (AOR)Chi-squareP value
*Adjusted odds ratios.
HbA1c1.761.134 - 2.7416.660.010
Cholesterol1.0181.006 - 1.03112.78< 0.001