Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Letter to the Editor

Volume 7, Number 6, December 2017, pages 197-198


Practical Diagnostic Algorithm for Pituitary Tumors: What Is New in the 2017 WHO Classification?

Figure

Figure 1.
Figure 1. New practical approach to diagnostic pituitary pathology. ACTH: adrenocorticotropic hormone; α-SU: alpha-subunit; β-FSH: follicle-stimulating hormone subunit beta; β-LH: luteinizing hormone subunit beta; β-TSH: thyroid-stimulating hormone subunit beta; DG: densely granulated; GH: growth hormone; IHC: immunohistochemistry; LMWCK: low-molecular-weight cytokeratin; PAS: periodic acid Schiff; PIT1: pituitary-specific POU-class homeodomain transcription factor 1; PRL: prolactin; SF1: steroidogenic factor 1; SG: sparsely granulated; TPIT: T-box family member TBX19; TTF1: thyroid transcription factor 1. aAdenomas associated with an elevated risk for recurrence. Clinically aggressive adenomas: high mitotic index; high Ki-67; tumor invasion. bPreviously called silent subtype 3 adenoma.