Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc |
Journal website http://www.jofem.org |
Original Article
Volume 5, Number 1-2, April 2015, pages 179-183
Thyroid Hormones Protect Type 2 Diabetes Obese Patients Against Cardio-Metabolic Risk Factors
Tables
Variables | Women (n = 100) | Men (n = 50) | P value |
---|---|---|---|
*Significant. The results are expressed as number (%) and mean ± SD (median). | |||
Age (year) | 51.5 ± 4.3 (50) | 52.4 ± 4.6 (50) | 0.237 |
Family history of diabetes | 24 (24) | 16 (32) | 0.296 |
Duration of diabetes (year) | 3.15 ± 1.60 (3) | 3.02 ± 1.48 (3) | 0.622 |
Weight (kg) | 97.5 ± 9 (94.5) | 92.7 ± 10.3 (89) | 0.006* |
Height (m) | 1.63 ± 0.045 (1.62) | 1.62 ± 0.039 (1.61) | 0.165 |
Body mass index (kg/m2) | 36.57 ± 2.15 (36.73) | 35.16 ± 2.54 (34.33) | 0.001* |
Waist circumference (cm) | 90.34 ± 7.4 (87.5) | 88.3 ± 8.4 (86) | 0.147 |
Waist/height ratio | 0.553 ± 0.036 (0.55) | 0.554 ± 0.042 (0.525) | 0.178 |
Variables | Women (n = 100) | Men (n = 50) | P value |
---|---|---|---|
The results are expressed as number and mean ± SD. | |||
Fasting serum glucose (mg/dL) | 210.2 ± 35.7 | 211.6 ± 33.2 | 0.806 |
Glycosylated hemoglobin (HbA1c %) | 8.1 ± 0.6 | 8.1 ± 0.7 | 0.755 |
Arterial blood pressure (mm Hg) | |||
Systolic | 135.2 ± 8.5 | 135.9 ± 8.7 | 0.653 |
Diastolic | 85.2 ± 4.7 | 86 ± 4.6 | 0.303 |
Mean | 101.8 ± 4.8 | 102.6 ± 5.1 | 0.368 |
Pulse pressure | 50.0 ± 8.4 | 49.9 ± 7.8 | 0.908 |
Fasting serum lipid profile | |||
Triglycerides (mg/dL) | 195.3 ± 83.0 | 184.1 ± 76.0 | 0.408 |
Total cholesterol (mg/dL) | 211.1 ± 68.2 | 203.5 ± 60.5 | 0.487 |
High density lipoprotein (mg/dL) | 51.6 ± 11.2 | 54.1 ± 11.0 | 0.195 |
Atherogenic lipoprotein (mg/dL) | 150.1 ± 67.6 | 128.9 ± 60.6 | 0.309 |
Atherogenic index | 0.553 ± 0.271 | 0.509 ± 0.254 | 0.338 |
High sensitivity C-reactive protein (mg/L) | 5.0 ± 0.66 | 4.9 ± 0.65 | 0.580 |
Variables | Women (n = 100) | Men (n = 50) | P value |
---|---|---|---|
*Significant. The results are expressed as number (%) and mean ± SD (median). | |||
Thyroid stimulating hormone (TSH) | |||
< 0.3 mIU/L | 18 (18) | 13 (26) | 0.253 |
> 0.6 mIU/L | 68 (68) | 30 (60) | 0.331 |
Mean ± SD (median) | 6.2 ± 5.2 (7.1) | 4.83 ± 4.24 (5.57) | 0.096 |
Thyroxin (T4) | |||
< 60 nmol/L | 22 (22) | 8 (16) | 0.386 |
> 140 nmol/L | 11 (11) | 8 (16) | 0.385 |
Mean ± SD (median) | 96.5 ± 35.1 (98.5) | 105.5 ± 33.8 (122) | 0.133 |
Triiodothyronine (T3) | |||
< 0.9 nmol/L | 19 (19) | 4 (8) | 0.163 |
> 2.5 nmol/L | 42 (42) | 30 (60) | 0.037* |
Mean ± SD (median) | 2.14 ± 1.2 (2.2) | 2.34 ± 1.07 (2.7) | 0.301 |
Variables | Women (n = 100) | P value | Men (n = 50) | P value |
---|---|---|---|---|
*Significant. The results are expressed as correlation coefficient (r). | ||||
Thyroid stimulating hormone (TSH) versus | ||||
Body mass index | 0.429 | 0.000* | 0.536 | 0.000* |
Waist circumference | 0.484 | 0.000* | 0.716 | 0.000* |
Mean arterial blood pressure | 0.219 | 0.028* | 0.445 | 0.001* |
Fasting serum glucose | 0.071 | 0.482 | 0.244 | 0.087 |
Glycosylated hemoglobin (HBA1c %) | 0.273 | 0.006* | 0.318 | 0.024* |
Fasting serum triglycerides | 0.545 | 0.000* | 0.761 | 0.000* |
Fasting serum high density lipoprotein | -0.469 | 0.000* | -0.809 | 0.000* |
High sensitivity C-reactive protein | 0.025 | 0.804 | 0.143 | 0.321 |
Thyroxine (T4) versus | ||||
Body mass index | -0.576 | 0.000* | -0.812 | 0.000* |
Waist circumference | -0.811 | 0.000* | -0.819 | 0.000* |
Mean arterial blood pressure | -0.496 | 0.000* | -0.534 | 0.000* |
Fasting serum glucose | -0.101 | 0.317 | -0.371 | 0.007* |
Glycosylated hemoglobin (HBA1c %) | -0.334 | 0.000* | -0.099 | 0.493 |
Fasting serum triglycerides | -0.843 | 0.000* | -0.850 | 0.000* |
Fasting serum high density lipoprotein | 0.790 | 0.000* | 0.821 | 0.000* |
High sensitivity C-reactive protein | -0.282 | 0.004* | -0.473 | 0.000* |
Triiodothyronine (T3) versus | ||||
Body mass index | -0.475 | 0.000* | -0.710 | 0.000* |
Waist circumference | -0.668 | 0.000* | -0.775 | 0.000* |
Mean arterial blood pressure | -0.351 | 0.000* | -0.430 | 0.001* |
Fasting serum glucose | -0.190 | 0.058 | -0.436 | 0.001* |
Glycosylated hemoglobin (HBA1c %) | -0.318 | 0.001* | -0.314 | 0.026* |
Fasting serum triglycerides | -0.760 | 0.000* | -0.826 | 0.000* |
Fasting serum high density lipoprotein | 0.704 | 0.000* | 0.820 | 0.000* |
High sensitivity C-reactive protein | -0.301 | 0.002* | -0.378 | 0.007* |