Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
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Case Report

Volume 5, Number 1-2, April 2015, pages 184-188

Soft Tissue Metastasis of Parathyroid Carcinoma: Description of a Difficult Case


Figure 1.
Figure 1. (a) Cervical sonography (US) - a nodular lesion was found contiguous to the lower right pole of the thyroid gland. (b) Sestamibi scintigraphy - positive late fixation at the right lower pole of the thyroid.
Figure 2.
Figure 2. Hematoxylin and eosin staining (H&E) of atypical adenoma of the left parathyroid named (2) in the text. (a) The adenoma was surrounded by a fibrous capsule with septa (× 10). (b) The lesion was composed of nests of chief cells with clear cytoplasm and moderate cytological atypia (× 400).
Figure 3.
Figure 3. Metastasis in the right thigh. (a) Macroscopically the tumor was nodular, white and with a fleshy consistence. (b) The lesion was composed of cells with abundant clear and vacuolized cytoplasm, with marked cellular atypia; numerous mitotic figures were found (H&E, × 400). Focal immunostaining with cytokeratin cocktail AE1/AE3 (c) and PTH (d) was found.
Figure 4.
Figure 4. Sestamibi scintigraphy - hyperfixation of the radionuclide at the outer side of the right thigh.