Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc |
Journal website http://www.jofem.org |
Original Article
Volume 4, Number 4, August 2014, pages 101-109
Autoimmune Polyglandular Syndrome Type II: Epidemiological, Clinical and Immunological Data
Figures
Tables
Diseases | Present study (106 cases) | Dittmar and Kahaly [12] (151 cases) | Weyermann et al [13] (31 cases) |
---|---|---|---|
Thyroid (%) | 93.4 | 65.5 | 97 |
Type 1 DM (%) | 62.3 | 60.9 | 35 |
Addison (%) | 36.8 | 18.5 | 23 |
Gonadal failure (%) | 11.3 | 5.3 | 16.1 |
Hypophysitis (%) | 5.6 | 0 | 0 |
Vitiligo (%) | 5.6 | 19.9 | 19.3 |
Alopecia (%) | 2.8 | 6 | 0 |
Sjogren’s syndrome (%) | 2.8 | 0 | 0 |
Pernicious anemia (%) | 1.8 | 5.3 | 16.1 |
Celiac disease (%) | 1.8 | 0 | 0 |
Autoimmune hepatitis (%) | 0.9 | 0 | 0 |
Immune thrombocytopenia (%) | 0.9 | 0 | 0 |
Autoantibodies against | Present study (106 cases) | Dittmar and Kahaly [12] (151 cases) |
---|---|---|
TPO (%) | 67.6 | 78 |
TSH-R (%) | 58 | 48 |
Tg (%) | 43.3 | 50 |
Parietal gastric cell (%) | - | 54 |
GAD (%) | 51.8 | 51 |
ICA (%) | 5.6 | 23 |
Insulin (%) | - | 42 |
Adrenal cortex (%) | 9.7 | 26 |
Ovarian (%) | 8.8 | - |