Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc |
Journal website http://www.jofem.org |
Original Article
Volume 5, Number 3, June 2015, pages 215-219
Cardiorespiratory Fitness Impact on All-Cause Mortality in Prediabetic Veterans
Figure
Tables
Least-fit (< 5.8 METs) | Low-fit (5.8 - 7 METS) | Moderate-fit (7.1 - 8.4 METs) | High-fit (≥ 8.5 METs) | |
---|---|---|---|---|
Age, BMI, total cholesterol, triglycerides, LDL-C and HDL-C are expressed as means ± SD. Hypertension defined as a systolic blood pressure > 130 mm Hg or a diastolic blood pressure > 80. Dyslipidemia defined as a total cholesterol > 200 mg/dL, LDL > 130 mg/dL or triglyceride > 199 mg/dL. | ||||
Number of patients | 289 | 292 | 265 | 272 |
Events | 101 (34.9%) | 66 (22.6%) | 48 (18.1%) | 36 (13.2%) |
Age | 65.7 ± 10.2 | 60.3 ± 10.2 | 56.7 ± 9.5 | 52.4 ± 8.5 |
BMI | 30.4 ± 6.6 | 30.6 ± 5.5 | 30.2 ± 5.1 | 28.4 ± 4.1 |
Gender | ||||
Male | 272 | 276 | 255 | 263 |
Female | 17 | 16 | 10 | 9 |
Race | ||||
White | 75 | 67 | 76 | 72 |
Black or other | 214 | 225 | 189 | 199 |
Hypertension | 223 (77.2%) | 214 (73.3%) | 176 (66.4%) | 157 (57.9%) |
Smoking | 47 (24.0%) | 55 (25.9%) | 39 (21.7%) | 37 (19.7%) |
Dyslipidemia | 109 (38.8%) | 124 (42.8%) | 117 (45.0%) | 108 (40.6%) |
Total cholesterol (mg/dL) | 187.7 ± 43.0 | 193.7 ± 40.8 | 195.6 ± 49.5 | 196.0 ± 37.9 |
Triglycerides (mg/dL) | 162.0 ± 175.3 | 148.0 ± 110.1 | 167.3 ± 198.5 | 135.4 ± 98.0 |
LDL-C (mg/dL) | 113.7 ± 34.3 | 121.2 ± 47.1 | 120.5 ± 40.1 | 122.1 ± 34.0 |
HDL-C (mg/dL) | 47.3 ± 13.3 | 48.5 ± 14.2 | 47.8 ± 13.9 | 50.3 ± 14.6 |
HR | CI | P-value | |
---|---|---|---|
Using lowest-fit as a reference, adjusted HRs for mortality were determined for contributions by age and presence of CVD. | |||
Age | 1.019 | 1.005 - 1.032 | 0.006 |
CVD | 2.018 | 1.519 - 2.681 | < 0.001 |
Lowest-fit (< 5.8 METs) | 1.000 | Reference | Reference |
Low-fit (5.8 - 7 METs) | 0.683 | 0.496 - 0.941 | 0.020 |
Moderate-fit (7.1 - 8.4 METs) | 0.599 | 0.413 - 0.867 | 0.007 |
High-fit (> 8.5 METs) | 0.463 | 0.304 - 0.705 | < 0.001 |
P-value | |
---|---|
Cardiovascular Medications refers to the presence of one of the following classes of medications at the time of ETT-beta blocker, calcium channel blocker, ACE inhibitor, angiotensin receptor blocker, diuretic, aspirin or statin. | |
BMI | 0.360 |
Cardiovascular medications | 0.468 |
Smoking status | 0.154 |
Hypertension | 0.774 |