![Figure 2.](http://www.jofem.org/tables/jem251w-g002.jpg)
Figure 2. (A) Effects of interleukin-6 (IL-6) and tocilizumab on adiponectin production in human adipocytes. Cells were differentiated for 12 days, and then treated without (control) or with 10 µg/mL IL-6 antibody, and/or 100 µg/mL, or 10 mg/mL tocilizumab. Data are presented as means ± SEM of at least four independent experiments. *P < 0.05; **P < 0.01 vs. control. Pio: pioglitazone. (B) Effects of interleukin-6 (IL-6) and tocilizumab on fatty acid-binding protein 4 levels in human adipocytes. Cells were differentiated for 12 days and treated without (control) or with 10 µg/mL IL-6 antibody, and/or 100 µg/mL, 10 mg/ml or tocilizumab. Data are expressed as means ± SEM of at least four independent experiments.*P < 0.05; **P < 0.01 vs. control. Pio: pioglitazone. (C) A representative western blot of fatty acid-binding protein 4 expression in human adipocytes treated without (control) or with 10 µg/mL interleukin-6 antibody, and/or 100 µg/mL, or 10 mg/mL tocilizumab. Pio: pioglitazone.